Wheat Germ Coated Surfaces
Wheat Germ Lectin, belonging to the lectins family, is a Hemagglutinin obtained from the common wheat germ Triticum Vulgaris. It is well known that lectins have been used extensively for the isolation of glyco-conjugates and glycoproteins with specific carbohydrate structures.
Wheat Germ Lectin shows specific affinity for molecules containing N-acetyl-D-glucosamine residue.
Wheat Germ Lectin coated surfaces offer a powerful and sensitive instrument for binding in specific way the carbohydrate fraction of glycoproteins, enzymes and cell membranes.
The optical properties of polystyrene remain unchanged, allowing to use the modified surface as powerful tool for diagnostic assays.
Example of applications:
- studies of surfaces of normal and transformed cells
- glycoprotein purification including membrane glycoproteins
- studies of cell surface changes during development and the cell cycle