Concanavalin A Coated Surfaces
Concanavalin A, belonging to the lectins family, is a Hemagglutinin from the common jack bean Canavalia ensiformis. It is well known that lectins have been used extensively for the isolation of glyco-conjugates and glycoproteins with specific carbohydrate structures.
Concanavalin A shows specific affinity for molecules containing α-D-mannopyranosyl , α-D-glucopyrannosyl and sterically related.
Concanavalin A coated surfaces offer a powerful and sensitive instrument for binding in specific way the carbohydrate fraction of glycoproteins, enzymes and cell membranes.
The optical properties of polystyrene remain unchanged, allowing to use the modified surface as powerful tool for diagnostic assays.
Example of applications:
- interaction with glycoproteins ,glycopeptides and enzyme-antibody conjugates
- polysaccharides and glycolipids
- interaction with cellular membranes, hormones and hormone receptors